Figure 3.
Percent suppression of the TNFα-induced NF-κB activation caused by glucocorticoids at 1 nM concentration as a function of consensus glucocorticoid receptor affinity (log Kd, equivalent to the log of the commonly used relative receptor binding affinity, rRBA, scales). Data are average of five independent experiments in quadruplicates using TNFα stimulation in the presence of the listed glucocorticoids (1 nM).