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. 2014 Jun 3;14:395. doi: 10.1186/1471-2407-14-395

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Copyright © 2014 Hanemann et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Immunostaining for E-cadherin. A) Immunostaining for E-cadherin in normal oral mucosa. B) Strong membranous immunostaining in the oral basaloid squamous cell carcinoma (BSCC). C) Most neoplastic cells of well to moderately differentiated squamous cell carcinoma (W/MSCC) showed strong membranous immunopositivity. D) Poorly differentiated squamous cell carcinoma (PDSCC) showed weak membranous immunostaining. (A, B, C and D, immunohistochemistry E-cadherin; original magnifications, A, B and D, ×400; C, ×100).