Table 2.
Variable | Hazard Ratio (95% CI) | P Value |
---|---|---|
Age at HSCT | ||
Adult | 1.0 | <.001 |
Pediatric | 3.0 (1.6–5.6) | |
Stem cell source | ||
Peripheral blood | 1.0 | |
Bone marrow | 1.0 (0.4–2.4) | .96 |
Cord blood | 1.4 (0.6–3.2) | .42 |
T-cell depletion | ||
Conventional | 1.0 | |
T-cell depleted (TCD) | 1.8 (0.8–3.3) | .15 |
Donor type | ||
Matched related | 1.0 | |
Matched unrelated | 0.8 (0.4–1.9) | .67 |
Mismatched | 1.1 (0.6–2.2) | .78 |
Acute GVHD | ||
Grade 0 – 1 | 1.0 | |
Grade 2 – 4 | 3.2 (1.6–6.3) | .001 |
Grade 0 – 2 | 1.0 | |
Grade 3 – 4 | 5.4 (2.7–11.0) | <.001 |
Abbreviations: ADV, adenovirus; CI, confidence interval; TCD, T-cell depleted; GVHD, graft versus host disease