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. 2014 May 25;15:10. doi: 10.1186/1471-2199-15-10

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Copyright © 2014 Calvo et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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KLF11 differentially couples to distinct chromatin co-factor systems. (A) Venn diagram of the overlap of genes significantly regulated by wild type KLF11 and its mutants. Genes that occur at the overlap of KLF11 and all three of its chromatin-coupling mutants were deemed as independent of the effects of chromatin de-coupling and therefore inherent to the protein itself. (B) Heatmap of the 11 KLF11-regulated genes that are dependent on interaction with all three chromatin coupling systems.