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. Author manuscript; available in PMC: 2014 Jun 9.
Published in final edited form as: Hum Immunol. 2002 Aug;63(8):657–664. doi: 10.1016/s0198-8859(02)00421-4

TABLE 2.

Normalized linkage disequilibrium between DRB1-DQB1 haplotypes and A alleles in AFBAC (n = 399)

Haplotype
DRB1 DQB1 HLA-A Dij D′ χ 2 P Value
0101 0501 0301 0.0149 0.223 10.24 0.001
0301 02 0101 0.0380 0.491 51.07 8.9 × 10−13
0301 02 0201 −0.0152 − 0.549 4.99 0.025
0401 0301 0201 0.0152 0.435 8.65 0.003
0404 0302 3101 0.0097 0.520 36.13 1.8 × 10−9
0701 02 2301 0.0038 0.262 3.97 0.046
0701 02 2902 0.0160 0.473 30.86 2.8 × 10−8
0701 02 3001 0.0042 0.367 6.05 0.014
1501 0602 0301 0.0245 0.215 16.40 5.1 × 10−5
1501 0602 2501 0.0065 0.248 4.50 0.034
1502 0601 0101 0.0043 0.705 7.55 0.006

Only haplotypes that occurred at least three times in the combined data set and exhibited significant linkage disequilibrium are listed.

Abbreviations: AFBAC = affected family-based controls; HLA = human leukocyte antigen.