TABLE 2.

HLA-C allele frequencies among T1D cases (transmitted) and controls (AFBAC) and proportion transmitted from heterozygote parents to T1D cases

HLA-C	Controls (%)	T1D (%)	Odds ratio	95% CI	p Value	Transmitted (%)
0102	2.3	2.3	1.02	(0.43–2.41)	NS	46.3
0202	4.5	3.3	0.72	(0.37–1.39)	NS	41.3
0206	0.3	0.2	0.70	(0.04–11.30)	NS	50.0
0302	0.5	0.0	—	—	NS	0.0
0303	2.5	6.3	2.60	(1.27–5.31)	0.008	63.4
0304	9.0	14.1	1.66	(1.09–2.52)	0.024	59.0
0305	0.0	0.1	—	—	NS	50.0
0314	0.0	0.2	—	—	NS	100.0
0401	10.5	6.8	0.62	(0.39–0.98)	0.049	40.5
0501	7.8	11.0	1.46	(0.93–2.29)	NS	57.2
0602	10.0	3.8	0.35	(0.21–0.61)	2.E-04	29.5
0606	0.0	0.1	—	—	NS	50.0
0701	13.0	25.6	2.30	(1.62–3.25)	2.E-05	61.5
0702	18.5	12.5	0.63	(0.44–0.90)	0.018	44.7
0704	1.8	1.1	0.60	(0.20–1.80)	NS	43.3
0801	0.0	0.1	—	—	NS	50.0
0802	4.3	1.6	0.36	(0.16–0.82)	0.013	31.7
1202	0.5	0.4	0.70	(0.10–5.02)	NS	40.0
1203	6.5	5.4	0.82	(0.48–1.40)	NS	46.9
1402	0.5	0.8	1.59	(0.30–8.46)	NS	57.1
1403	0.3	0.0	—	—	NS	0.0
1502	2.5	1.0	0.38	(0.13–1.09)	NS	32.4
1504	0.0	0.2	—	—	NS	50.0
1505	0.3	0.8	3.19	(0.36–27.95)	NS	75.0
1601	3.8	1.3	0.34	(0.14–0.83)	0.015	30.0
1602	0.3	0.4	1.41	(0.13–15.62)	NS	50.0
1604	0.0	0.1	—	—	NS	50.0
1701	0.5	0.7	1.41	(0.26–7.75)	NS	44.4

See Table 1 for abbreviations.