TABLE 3.

HLA-B and HLA-C haplotype frequencies among T1D cases (transmitted) and controls (AFBAC) and proportion transmitted from heterozygote parents to T1D cases (only haplotypes with frequencies above 0.5% in either T1D cases or controls are shown)

HLA-B	HLA-C	Controls (AFBAC) (%)	T1D (%)	Odds ratio	95% CI	p Value	Transmitted (%)
0702	0702	16.5	7.9	0.43	(0.29–0.65)	9.E-05	36.5
0705	1505	0.3	0.8	3.19	(0.36–27.95)	NS	75.0
0801	0701	9.3	21.0	2.60	(1.76–3.86)	8.E-06	63.0
1302	0602	1.5	0.7	0.47	(0.13–1.66)	NS	36.4
1401	0802	0.8	0.5	0.70	(0.14–3.50)	NS	43.8
1402	0802	3.3	1.1	0.32	(0.12–0.84)	0.017	28.6
1501	0303	1.0	4.2	4.37	(1.51–12.70)	0.004	74.2
1501	0304	2.3	6.9	3.21	(1.54–6.70)	0.001	69.6
1501	0401	0.5	0.6	1.24	(0.22–7.05)	NS	58.3
1801	0501	1.0	5.4	5.62	(1.97–16.08)	4.E-04	80.3
1801	0701	1.8	1.7	0.96	(0.36–2.56)	NS	55.9
1801	1203	2.0	1.4	0.70	(0.26–1.88)	NS	44.4
2703	0102	0.5	1.1	2.13	(0.43–10.59)	NS	60.0
2703	0202	1.8	2.4	1.37	(0.54–3.44)	NS	54.0
3501	0401	5.5	3.8	0.68	(0.37–1.24)	NS	41.8
3502	0401	1.8	0.1	0.05	(0.00–0.88)	0.004	6.3
3503	0401	0.5	0.8	1.59	(0.30–8.46)	NS	57.1
3701	0602	0.8	0.5	0.70	(0.14–3.50)	NS	35.7
3801	1203	2.5	1.9	0.74	(0.31–1.77)	NS	41.3
3901	0702	0.8	0.3	0.35	(0.05–2.50)	NS	25.0
3901	1203	0.5	1.0	1.95	(0.38–9.88)	NS	68.8
3906	0702	0.8	3.6	4.96	(1.47–16.78)	0.005	85.4
4001	0304	6.5	6.5	1.00	(0.60–1.69)	NS	50.7
4002	0202	1.0	0.3	0.26	(0.04–1.72)	NS	25.0
4402	0501	6.5	5.5	0.83	(0.49–1.42)	NS	46.3
4402	0704	0.8	0.9	1.18	(0.28–4.95)	NS	55.6
4403	0401	1.0	0.4	0.44	(0.09–2.14)	NS	25.0
4403	1601	3.5	0.8	0.22	(0.08–0.64)	0.003	22.5
4901	0701	0.8	1.0	1.30	(0.32–5.32)	NS	54.5
5001	0602	1.3	1.2	0.99	(0.31–3.13)	NS	46.7
5101	1402	0.5	0.7	1.41	(0.26–7.75)	NS	66.7
5101	1502	2.5	0.8	0.31	(0.10–0.96)	0.033	28.1
5301	0401	1.0	0.3	0.26	(0.04–1.72)	NS	25.0
5501	0303	1.3	0.6	0.49	(0.12–1.93)	NS	35.0
5601	0102	0.8	0.6	0.82	(0.17–3.86)	NS	43.8
5701	0602	5.0	0.4	0.08	(0.02–0.32)	5.E-06	9.6

See Table 1 for abbreviations.