TABLE 5.
Linkage disequilibrium between class II DRB1-DQB1 haplotypes and class I HLA-B alleles among controls
| DRB1 | DQB1 | HLA-B | DR-DQ frequency (%) |
HLA-B frequency (%) |
DR-DQ-B frequency (%) |
Dij | D ′ | p Value |
|---|---|---|---|---|---|---|---|---|
| 1501 | 0602 | 0702 | 15.79 | 16.54 | 9.27 | 0.067 | 0.506 | 1.8E-16 |
| 0301 | 02 | 0801 | 9.52 | 9.27 | 6.77 | 0.059 | 0.701 | 6.9E-36 |
| 0701 | 02 | 4403 | 10.28 | 4.76 | 3.51 | 0.030 | 0.707 | 6.6E-18 |
| 0101 | 0501 | 3501 | 7.52 | 7.27 | 1.75 | 0.012 | 0.180 | 1.1E-03 |
| 0701 | 02 | 1302 | 10.28 | 1.50 | 1.50 | 0.013 | 1.000 | 7.1E-12 |
| 0401 | 0302 | 1501 | 3.51 | 4.01 | 1.50 | 0.014 | 0.405 | 3.9E-13 |
| 1501 | 0602 | 1801 | 15.79 | 5.76 | 1.50 | 0.006 | 0.122 | NS |
| 1302 | 0604 | 4001 | 3.26 | 6.52 | 1.50 | 0.013 | 0.424 | 2.2E-08 |
| 0404 | 0302 | 4001 | 3.26 | 6.52 | 1.50 | 0.013 | 0.424 | 2.2E-08 |
| 0401 | 0301 | 4402 | 4.51 | 7.52 | 1.50 | 0.012 | 0.279 | 6.5E-05 |
| 0101 | 0501 | 0702 | 7.52 | 16.54 | 1.25 | 0.000 | 0.002 | NS |
| 1104 | 0301 | 1801 | 3.26 | 5.76 | 1.25 | 0.011 | 0.347 | 9.1E-07 |
| 1301 | 0603 | 3801 | 5.76 | 2.76 | 1.25 | 0.011 | 0.421 | 4.2E-08 |
| 0101 | 0501 | 4001 | 7.52 | 6.52 | 1.25 | 0.008 | 0.127 | 2.9E-02 |
| 0301 | 02 | 1801 | 9.52 | 5.76 | 1.00 | 0.005 | 0.087 | NS |
| 1101 | 0301 | 3501 | 4.76 | 7.27 | 1.00 | 0.007 | 0.149 | 2.6E-02 |
| 1101 | 0301 | 5101 | 4.76 | 4.01 | 1.00 | 0.008 | 0.213 | 2.1E-04 |
| 1302 | 0604 | 0702 | 3.26 | 16.54 | 0.75 | 0.002 | 0.078 | NS |
| 0701 | 02 | 1402 | 10.28 | 3.26 | 0.75 | 0.004 | 0.143 | NS |
| 0701 | 02 | 3501 | 10.28 | 7.27 | 0.75 | 0.000 | 0.001 | NS |
| 0401 | 0301 | 4001 | 4.51 | 6.52 | 0.75 | 0.005 | 0.109 | NS |
| 1501 | 0602 | 4402 | 15.79 | 7.52 | 0.75 | −0.004 | −0.367 | NS |
| 1301 | 0603 | 4402 | 5.76 | 7.52 | 0.75 | 0.003 | 0.060 | NS |
| 1201 | 0301 | 4402 | 1.75 | 7.52 | 0.75 | 0.006 | 0.382 | 6.5E-04 |
| 1501 | 0602 | 5101 | 15.79 | 4.01 | 0.75 | 0.001 | 0.035 | NS |
See Table 1 for abbreviations.