Table 2. Genes involved in CoQ synthesis in S. cerevisiae, S. pombe, humans, and A. thaliana.
S. cerevisiae | S. pombe | H. sapiens (accession #) | Arabidopsis (systematic name) | Enzyme (function) |
COQ1 | dps1-dlp1 | HsPDSS1(AI590245)-HsPDSS2(BI551760) | AtSPS3 (At2g34630) | Polyprenyl diphosphate synthase |
COQ2 | ppt1/coq2 | HsCOQ2 (BF026793) | AtPPT1 (At4g23660) | PHB-polyprenyldiphosphate transferase |
COQ3 | coq3 | HsCOQ3 (AF193016) | AtCOQ3 (At2g30920) | O-Methyltransferase |
COQ4 | coq4 | HsCOQ4 (BQ685658) | AtCOQ4 (At2g03690) | Unknown |
COQ5 | coq5 | HsCOQ5 (BC004916) | AtCOQ5 (At5g57300) | C-Methyltransferase |
COQ6 | coq6 | HsCOQ6 (BQ668512) | AtCOQ6 (At3g24200) | C5-Hydroxylation |
COQ7 | coq7 | HsCOQ7 (AF032900) | - | Monooxygenase |
COQ8/ABC1 | coq8 | HsCOQ8/ADCK3 (BC005171) | AtCOQ8 (At4g01660) | Protein kinase |
COQ9 | coq9 | HsCOQ9 (BC064946) | AtCOQ9 (At1g19140) | Unknown |