Table 1.
Cell culture studies performed with Adipose Derived Stem Cells and Platelet Rich Plasma.
| ADIPOSE DERIVED STEM CELLS (ADSCs) | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| BIOLOGICAL EFFECTS (PRP vs FBS) | |||||||
|
| |||||||
| Stemness | |||||||
|
| |||||||
| Author, year, [reference] | Platelet count Pool or single donor | Proliferation | Migration | Immune modulation | Chondr. | Adipo. | Osteo. |
| Van Pham 2013 [7] | Super high (6x) Single donor |
Enhanced | - | - | Enhanced | Similar | Similar |
| Hildner 2013 [8]* | - - |
Enhanced | - | - | Enhanced | - | - |
| Chen L. 2012 [9]# | Super high (6x) Single donor |
Enhanced | - | - | - | - | Enhanced |
| Cervelli 2012 [10] | - Pool |
Enhanced | - | - | - | Enhanced with insulin | - |
| Sell 2011 [11]# | High (3.82x) Pool |
Enhanced | Enhanced | - | - | - | |
| Shih 2011 [12]* | - Single donor |
Enhanced | - | - | Enhanced | Similar | Similar |
| Cholewa 2011 [13]* | Super high (6.2x) Pool |
Enhanced | - | - | - | Similar | Similar |
| Chieregato 2011 [14]* | Moderate (2x) - |
Enhanced | - | - | Similar | Enhanced | Enhanced |
| Castegnaro 2011 [15]* | Moderate (2.74x) Pool |
Enhanced | - | Enhanced | - | Similar | Similar |
| Souza Blande 2009 [16]* | Moderate (3.64x) Single donor |
Enhanced | - | - | - | Similar | Similar |
| Kakudo 2008 [17] | Super High (7.9x) Single donor |
Enhanced | - | - | - | - | - |
| Kocaoember 2007 [18]* | Super high (10x) Pool |
Enhanced | - | - | - | Similar | Similar |
*
Articles performing long term expansion studies;
#
Articles performing 3D studies.
Abbreviations: ADSCs, Adipose Derived Stem Cells; PRP, Platelet Rich plasma; FBS, Fetal bovine serum; Chondr, Chondrogenic; Adipo., Adipogenic; Osteo., Osteogenic.