Table 3.
Cell culture studies performed with Bone Marrow derived Stem Cells and Adipose Derived Stem Cells or Umbilical Cord Derived Mesenchymal Stem Cells (UCMSCs) and Platelet Rich Plasma.
| SEVERAL STEM CELL SOURCES | ||||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| BIOLOGICAL EFFECTS (PRP vs FBS) | ||||||||
|
| ||||||||
| Stemness | ||||||||
|
| ||||||||
| Author, year, [reference] | Platelet count Pool or single donors | Cell source | Proliferation | Migration | Immune modulation | Chondr. | Adipo. | Osteo. |
| Hemeda 2013 [56] | Super high (6.2x) Pool |
BMSCs and ADSCs | Decreased at high heparin concentrations | - | - | - | Decreased at high heparin concentrations | Decreased at high heparin concentration |
| Lohmann 2012 [57] | Super high (6.2x) Single donors |
BMSCs and ADSCs | Enhanced | - | - | - | Similar | Decreasedwith old d. |
| Menard 2013 [3] | - Pool |
BMSCs and ADSCs | - | - | Enhanced in ADSCs | - | - | - |
| Torensma 2013 [58]* | - Pool |
BMSCs and ADSCs | - | Decreased | - | - | - | |
| Jenhani 2011 [59]* | - Pool |
UCMSCs and BMSCs | Enhanced | - | - | - | - | - |
| Crespo-Diaz 2011 [60]* | - Pool |
BMSCs and ADSCs | Enhanced | - | - | Similar | Similar | Similar |
| Avanzini 2009 [61]* | Super high (10x) Pool |
UCMSCs and BMSCs | - | - | - | - | - | - |
| Reinisch 2007 [62] | Moderate (3.8x) Pool |
UCMSCs | Decreased in late passages | - | Similar | Similar | Decreased | Similar |
*
Articles performing long term expansion studies
Abbreviations: ADSCs, Adipose Derived Stem Cells; BMSCs, Bone Marrow derived Stem Cells; UCMSCs, Umbilical Cord Derived Mesenchymal Stem Cells; PRP: Platelet Rich plasma; FBS: Fetal bovine serum; Chondr.: Chondrogenic; Adipo.: Adipogenic; Osteo.: Osteogenic.