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Tumorigenicity experiments of CD133+ SFCs and parental cells in Balb/c-nu mice (n=4 per group).
| Cell type | Cell number | Tumor incidence | Latency (days) |
|---|---|---|---|
| Parental cells | 5×104 | 0/4 | - |
| 1×105 | 0/4 | - | |
| 2×105 | 3/4 | 37 | |
| 5×105 | 4/4 | 29 | |
| 1×106 | 4/4 | 7 | |
| CD133+ SFCs | 5×102 | 0/4 | - |
| 1×103 | 3/4 | 27 | |
| 5×103 | 4/4 | 16 | |
| 1×104 | 4/4 | 10 | |
| 5×104 | 4/4 | 7 |
CD133, cluster of differentiation 133; SFCs, sphere-forming cells.
