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. 2014 Mar 11;15(6):688–698. doi: 10.4161/cbt.28413

Table 1. Hazard ratios for OS and DFS based upon dCK expression (high vs. low [reference level]) patients treated with gemcitabine or 5-FU.

  Total patients analyzed (n = 165) Gemcitabine arm (n = 76) 5-FU arm (n = 89)
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Univariable analysis DFS 0.78 (0.57, 1.08) P = 0.13 0.96 (0.60, 1.54) P = 0.87 0.66 (0.42, 1.03) P = 0.065
OS 0.66 (0.47, 0.93) P = 0.016 0.83 (0.51, 1.36) P = 0.45 0.56 (0.35, 0.88) P = 0.012
Multivariable analysis DFS 0.75 (0.54–1.04) P = 0.08 0.96 (0.60, 1.54) P = 0.87 0.60 (0.38, 0.95) P = 0.027
OS 0.61 (0.44, 0.86) P = 0.0044 0.79 (0.48, 1.30) P = 0.35 0.53 (0.33, 0.85) P = 0.0078