Table 1. Hazard ratios for OS and DFS based upon dCK expression (high vs. low [reference level]) patients treated with gemcitabine or 5-FU.
Total patients analyzed (n = 165) | Gemcitabine arm (n = 76) | 5-FU arm (n = 89) | |||||
---|---|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | ||
Univariable analysis | DFS | 0.78 (0.57, 1.08) | P = 0.13 | 0.96 (0.60, 1.54) | P = 0.87 | 0.66 (0.42, 1.03) | P = 0.065 |
OS | 0.66 (0.47, 0.93) | P = 0.016 | 0.83 (0.51, 1.36) | P = 0.45 | 0.56 (0.35, 0.88) | P = 0.012 | |
Multivariable analysis | DFS | 0.75 (0.54–1.04) | P = 0.08 | 0.96 (0.60, 1.54) | P = 0.87 | 0.60 (0.38, 0.95) | P = 0.027 |
OS | 0.61 (0.44, 0.86) | P = 0.0044 | 0.79 (0.48, 1.30) | P = 0.35 | 0.53 (0.33, 0.85) | P = 0.0078 |