Table 3. Islet transplantation outcomes based on non-collagenolytic enzyme used.
| Patient |
Islet mass (IE/kg) |
Pre-Tx insulin (u/kg/day) |
1 mo post Tx insulin (u/kg/day) |
Basal c-peptide (nmol/L) |
Stimulated c-peptide (nmol/L) |
HbA1c 1 mo pre-Tx |
HbA1c 1 mo post-Tx |
SUITO index |
|---|---|---|---|---|---|---|---|---|
| haNP 1 | 6,410 | 0.65 | 0.15 | 0.72 | Not done | 9.6 | 7.2 | 33.2 |
| haNP 2 | 6,445 | 0.69 | 0.25 | 0.80 | Not done | 7.8 | 6.8 | 49.1 |
| MTF 1 | 7,188 | 0.46 | 0.00 | 0.81* | 2.13* | 10.0 | 7.9 | 93.3 |
| MTF 2 | 6,699 | 0.71 | 0.38 | 0.48 | 1.02 | 8.6 | 7.5 | 30.2 |
| MTF 3 | 7,249 | 0.42 | 0.00 | 0.41 | 0.58 | 8.2 | 7.1 | 35.7 |
| MTF 4 | 5,937 | 0.51 | 0.25 | 0.47 | 1.19 | 8.9 | 7.7 | 29.6 |
| MTF 5 | 6,050 | 0.63 | 0.34 | 0.54 | 1.69 | 8.3 | 6.9 | 34.4 |
*
Values are from 3 mo post-transplant assessment.