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Figure 2. Regulation of Rho GTPase activity by endothelial-enriched GEFs and GAPs. A schematic representation of Rho GTPase regulation by GEFs (green), GAPs (red), and GDIs. Listed are GEFs and GAPs that are above 5-fold higher expressed in endothelial cells compared with cells from other tissues. Rho-GDIα is the only GDI that is strongly expressed in HUVECs.
