Table 2. Essentiality of S. pombe nucleoporins.
Name | ORF name | Individual analyses (references) | Comprehensive deletion analysis (Kim et al.)46 | This study | |
---|---|---|---|---|---|
spCut11 | SPAC1786.03 | e | (West et al.)26 | e | |
spPom34 /Mug31 | SPAC1002.02 | n | n | ||
spPom152 | SPBC29A10.07 | n | n | ||
spTts1 | SPBC1539.04 | n | (Zhang et al.)41 | n | |
spEly5 | SPBC29A10.06c | n | (Bilokapic and Schwartz)33 | n | n |
spNup37 | SPAC4F10.18 | n | (Bilokapic and Schwartz)33 | n | n |
spNup85 | SPBC17G9.04c | e | (Baï et al.; Chen et al.)19,29 | e | |
spNup107 | SPBC428.01c | e | (Baï et al.; Chen et al.)19,29 | e | |
spNup120 | SPBC3B9.16c | n | (Baï et al.)19 | n | |
spNup131 | SPBP35G2.06c | n | (Baï et al.)19 | n | |
spNup132 | SPAC1805.04 | n | (Baï et al.; Chen et al.)19,29 | n | |
spNup189c | SPAC1486.05 | e | |||
spSeh1 | SPAC15F9.02 | n | (Baï et al.; Chen et al.)19,29 | n | |
spNup97 /Mug87 | SPCC1620.11 | e | (Cho et al.)30 | e | |
spNpp106 | SPCC1739.14 | n | (Yoon et al.)25 | n | |
spNup184 | SPAP27G11.10c | n | (Whalen et al.)28 | n | |
spNup186 | SPCC290.03c | e | (Chen et al.)29 | e | |
spNup155 | SPAC890.06 | n | e | ||
spNup40 | SPAC19E9.01c | n | (Chen et al.)29 | n | |
spNsp1 | SPAC26A3.15c | e | (Chen et al.)29 | e | |
spNup44 | SPBC19G7.15 | e | (Chen et al.)29 | e | |
spNup45 | SPAC22G7.09c | e | (Chen et al.)29 | e | |
spNup82 | SPBC13A2.02 | n | e | ||
spNup146 | SPAC23D3.06c | e | (Chen et al.)29 | e | |
spNup60 | SPCC285.13c | n | n | ||
spNup61 | SPCC18B5.07c | n | (Chen et al.)29 | n | |
spNup124 | SPAC30D11.04c | n | (Balasundaram et al.)27 | n | |
spNup211 | SPCC162.08c | e | (Chen et al.)29 | e | |
spNup189n | SPAC1486.05 | e | |||
spRae1 | SPBC16A3.05c | e | (Brown et al.)24 | e | |
spAmo1 | SPBC15D4.10c | n | (Pardo and Nurse)48 | n |
Essential nucleoporins are shown in bold according to individual analyses and this study. “e” and “n” represent “essential” and “non-essential,” respectively.