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Figure 6. API-2 prevents the nuclear accumulation of cyclin D1. Percentages of 31FR-WI-38 cells (doses are indicated) double positive for cyclin D1 and PCNA were determined for cells treated with API-2 (closed circles) and for cells not treated with API-2 (open circles). Cells were analyzed 24 h (left panel) or 7 d (right panel) after drug treatment.
