Table 3. Cancer subtypes with CNAs in breast cancer patients.
CNA** (young group) | CNA** (old group) | P | |||
---|---|---|---|---|---|
Positive | Negative | Positive | Negative | ||
Luminal A type * | 37 (19%) | 154 (81%) | 26 (8%) | 284 (91%) | 0.000 |
Luminal B type* | 105 (28%) | 271 (72%) | 61(15%) | 358(85%) | 0.000 |
Her2 overexpression type | 31 (46%) | 37 (54%) | 27(34%) | 53 (66%) | 0.142 |
TNBC type | 81 (56%) | 63 (44%) | 35(36%) | 61(64%) | 0.003 |
(1) **CNA: Copy number aberrations; (2) Luminal A type*: the followings are excluded: 1 Rb1 amplification event in the young breast cancer positive group, 1 Rb1 amplification event and 1 CCND1 deletion event in the old breast cancer positive group. TNBC type*: the followings are excluded: 1 Rb1 amplification event, 1 CHEK2 amplification event, 1 CCND1 and 1 C-myc deletion events in the young positive; 1 C-myc deletion event in the old positive group.