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. 2014 Mar 7;13(9):1424–1439. doi: 10.4161/cc.28402

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Copyright © 2014 Landes Bioscience

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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graphic file with name cc-13-1424-g11.jpg — Figure 11. Irradiated E1A + E1B cells show suppression of mTORC1 and mTORC2 and activation of autophagy. Western blot analysis of phosphorylation of S6 ribosomal protein and 4E-BP1 (A) and phosphorylation of Akt on Ser473 (B). The indicated numbers show the results of western blot densitometry. (C) Western blot analysis of LC3-I conversion to LC3-II. (D) Analysis of LC3 and LAMP1 colocalization in non-irradiated and IR-treated cells. Confocal images are shown.