Table 5. Multinomial logistic regression analysis of rs762623 with nationality included as a covariate.
Fibrosis stage | EST (SE) | OR (L95–U95) | P value |
---|---|---|---|
Stage 0 vs. stage 1 | 0.7632 (0.2631) | 2.145 (1.281–3.593) | 0.0037 |
Stage 0 vs. stage 2 | 1.1522 (0.3151) | 3.165 (1.707–5.869) | 0.0003 |
Stage 0 vs. stage 3 | 0.8175 (0.3279) | 2.265 (1.191–4.307) | 0.0127 |
Stage 0 vs. stage 4 | 0.6975 (0.4146) | 2.009 (0.891–4.527) | 0.0925 |
Stage 1 vs. stage 2 | 0.3890 (0.3066) | 1.476 (0.809–2.691) | 0.2045 |
Stage 1 vs. stage 3 | 0.05432 (0.3206) | 1.056 (0.563–1.979) | 0.8655 |
Stage 1 vs. stage 4 | −0.0657 (0.4079) | 0.936 (0.421–2.083) | 0.8720 |
Stage 2 vs. stage 3 | −0.3347 (0.3487) | 0.716 (0.361–1.417) | 0.3372 |
Stage 2 vs. stage 4 | −0.4548 (0.4287) | 0.635 (0.274–1.470) | 0.2888 |
Stage 3 vs. stage 4 | −0.1201 (0.4366) | 0.887 (0.377–2.087) | 0.7833 |
Multinomial logistic regression to determine the effect of rs762623 on the development of different stages of fibrosis in the combined UK and Finnish Cohort, with nationality included as a covariate. The reference level of fibrosis ranges from fibrosis stage 0 to 4. EST, estimate of the effect; SE, standard error of the estimate; OR odds ratio; L95 lower 95% confidence interval of the odds ratio; U95 upper 95% confidence interval of the OR.