Figure 4.

Distributions and correlation of regional V_T and K_b estimates. Results are reported for 2TCM (V_T, panel A) and 2TCM-1K (V_T and K_b, panels A and B, respectively). Homozygous high-affinity binders (HAB, 8 subjects) and heterozygous mixed-affinity binders (MAB, 10 subjects) are shown separately. (C) Correlation analysis of 2TCM versus 2TCM V_T estimates of HAB subjects (black diamonds) and MAB subjects (gray squares). The equations of the regression lines and the Pearson's correlation coefficients (R²) are reported in the same chart.