Table 1. Baseline variables.
| Variable | Entire group (n=138) | Good outcome (n=57) | Poor outcome (n=81) | Univariate P | Multivariate P |
|---|---|---|---|---|---|
| Baseline variables | |||||
| Age | 64.0±13.9 | 60.7±14.8 | 66.3±12.8 | 0.02 | |
| Baseline NIHSS | 17 (13–20) | 14 (9–18) | 17 (15–21) | <0.0001 | 0.0003 |
| Men (%) | 90 (65.2%) | 34 (59.6%) | 56 (69.1%) | 0.33 | |
| Diabetes (%) | 20 (14.5%) | 4 (7.0%) | 16 (19.8%) | 0.06 | 0.02 |
| HTN (%) | 67 (48.6%) | 21 (36.8%) | 46 (56.8%) | 0.03 | <0.05 |
| AF (%) | 45 (32.6%) | 22 (38.6%) | 23 (28.4%) | 0.28 | |
| HL (%) | 74 (53.6%) | 30 (52.6%) | 44 (54.3%) | 0.98 | |
| CHF (%) | 14 (10.1%) | 7 (12.3%) | 7 (8.6%) | 0.68 | |
| Previous stroke (%) | 19 (13.8%) | 3 (5.3%) | 16 (19.8%) | 0.03 | |
| Current smoking (%) | 43 (31.2%) | 18 (31.6%) | 25 (30.9%) | 0.92 | |
| Smoking history (%) | 25/78 (32.1%) | 10/30 (33.3%) | 15/48 (31.3%) | 0.95 | |
| Imaging findings | |||||
| Intracranial occlusion (%) | 0.02 | ||||
| ICA | 16 (11.6%) | 1 (1.8%) | 15 (18.5%) | ||
| MCA M1+ACA | 1 (0.7%) | 0% | 1 (1.2%) | ||
| MCA M1 | 78 (56.5%) | 36 (63.2%) | 42 (51.9%) | ||
| MCA M2 | 21 (15.2%) | 11 (19.3%) | 10 (12.3%) | ||
| ACA | 2 (1.4%) | 2 (3.5%) | 0% | ||
| None (isolated cervical) | 20 (14.5%) | 7 (12.3%) | 13 (16.0%) | ||
| Cervical ICA occlusion (%) | 51 (37%) | 20 (35.1%) | 31 (38.3%) | 0.84 | |
| Baseline DWI lesion volume (mL) | 14.4 (6.4–45.0) (n=101) | 10.3 (4.4–19.3) (n=46) | 19.8 (8.7–52.2) (n=55) | 0.001 | |
| Baseline MTT lesion volume (mL) | 173.7 (129.5–214.8) (n=80) | 153.4 (113.2–214.8) (n=40) | 179.8 (155.1–219.0) (n=40) | 0.12 | |
| Treatment data | |||||
| IV tPA (%) | 103 (74.6%) | 47 (82.5%) | 56 (69.1%) | 0.12 | |
| LSW to groin (min) | 238.5 (190–310) | 240 (190–310) | 235 (194–310) | 0.73 | |
| Stent retriever (%) | 39/131 (29.8%) | 15/53 (28.3%) | 24/78 (30.8%) | 0.91 | |
| Cervical stent (%) | 32/137 (23.4%) | 16/56 (28.6%) | 16 (19.8%) | 0.32 | |
| Modified TICI | 2b (0-3) | 3 (2a-3) | 2a (0-2b) | <0.0001 | 0.0001 |
| mTICI 2b-3 | 72 (52.2%) | 42 (73.7%) | 30 (37.0%) | <0.0001 | |
| LSW to TICI 2a-3 (minutes) | 330 (276–370) (n=90) | 320 (271–360) (n=47) | 340 (288–389) (n=43) | 0.14 | |
| Admission to groin (minutes) | 149.5 (114–194) | 154 (114–193) | 143 (111–198) | 0.78 | |
| Scan to groin (minutes) | 118 (91–162) | 125 (97–168) | 109 (90–160.5) | 0.29 | |
ACA, anterior cerebral artery; AF, atrial fibrillation; CHF, congestive heart failure; DWI, diffusion-weighted imaging; HL, hyperlipidemia; HTN, hypertension; ICA, internal carotid artery; IV, intraveneous; LSW, last seen well; MCA, middle cerebral artery; mTICI, modified TICI; MTT, mean transit time; NIHSS, National Institutes of Health Stroke Scale; TICI, thrombolysis in cerebral infarction; tPA, tissue plasminogen activator.