Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 May 23;5:3817. doi: 10.1038/ncomms4817

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/

PMC Copyright notice

(a) Inset: experiment diagram. Upper traces: pattern of electric stimuli applied with varied amplitudes to the presynaptic perforant fibres, as depicted. Lower traces: the corresponding somatic voltage recordings (colour-coded accordingly) show a characteristic one-cell example. (b) Somatic voltage traces in a expanded as shown by dashed lines; arrows depict spiking threshold values (V_T) that visibly increase with lower rates of perforant fibre excitation-induced somatic depolarization. (c) Multiple trials recorded, in an arbitrary sequence, in five individual cells show strong correlation between the rate of depolarization (set by the synaptic input strength) and the granule cell-spiking threshold (V_T). Experiments carried out at 33 °C.