Fig. 1.

Pareto chart showing significant effects of factors above the ‘Bonferroni Limit’ and ‘t-value Limit’ and insignificant effect of the factors below the ‘Bonferroni Limit’ and ‘t-value Limit’ X1 (pH), X2 (temperature), X3 (yeast extract), X4 (peptone), X5 (beef extract), X6 (sucrose), X7 (l-tyrosine), X8 (CuSO4), X9 (MgSO4), X10 (K2HPO4), and X11 (Thiamine)