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. 2014 Apr 18;2(5):576–591. doi: 10.1016/j.stemcr.2014.03.003

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© 2014 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

PMC Copyright notice

Transcriptome Profile of CS-Derived Clones

(A) Quantitative real-time PCR analysis for ISL-1, NKX2.5, Periostin, and SMA in CD90⁻ and CD90⁺ CS-derived clones.

(B) Hierarchical clustering analysis of the four CS-derived clones. Differential gene expression was determined using the mean for each sample of CD90⁻ clones versus CD90⁺ clones. Hierarchical clustering analysis was performed using Partek Genomic Suite software.

(C) Differential expression of genes upregulated (red) and downregulated (green). Blue line represents p value of <0.05.

(D) Pathway analysis using ingenuity pathway analysis (IPA). Significant enrichment of canonical pathways in CD90⁻ samples versus CD90⁺ samples (gray bars) is shown. Blue line represents ratio.

n = 6; ^∗p < 0.05.

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