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. 2013 Nov 15;27(6):851–862. doi: 10.1038/modpathol.2013.198

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Copyright © 2014 United States & Canadian Academy of Pathology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Co-expression analysis of herpesvirus saimiri DNA and related proteins in idiopathic pulmonary fibrosis. Each set of panels shows the RGB image (a, c, e, and g) and the Nuance-derived image (b, d, f, and h) after co-expression analysis of viral DNA (blue in the RGB image and fluorescent blue in the Nuance image) and the protein (DAB for a and c and fast red for e and g; each protein is fluorescent red in the Nuance image). Fluorescent yellow in b, d, f, and h reflects co-expression of the viral DNA and the protein; each image is at × 400. Herpesvirus saimiri DNA strongly co-expressed with thymidylate synthase (a, b), IL-17 (c and d), and cyclin D1 (e and f). e/f and g/h are serial sections in which the same cells were analyzed for co-expression for cyclin D1 and the herpesvirus saimiri DNA STP gene (e and f) and the terminal repeat sequence (g and h), respectively.

Co-expression analysis of herpesvirus saimiri DNA and related proteins in idiopathic pulmonary fibrosis. Each set of panels shows the RGB image (a, c, e, and g) and the Nuance-derived image (b, d, f, and h) after co-expression analysis of viral DNA (blue in the RGB image and fluorescent blue in the Nuance image) and the protein (DAB for a and c and fast red for e and g; each protein is fluorescent red in the Nuance image). Fluorescent yellow in b, d, f, and h reflects co-expression of the viral DNA and the protein; each image is at × 400. Herpesvirus saimiri DNA strongly co-expressed with thymidylate synthase (a, b), IL-17 (c and d), and cyclin D1 (e and f). e/f and g/h are serial sections in which the same cells were analyzed for co-expression for cyclin D1 and the herpesvirus saimiri DNA STP gene (e and f) and the terminal repeat sequence (g and h), respectively.