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. 2014 May 19;111(22):E2271–E2280. doi: 10.1073/pnas.1318262111

Fig. 4.

Fig. 4.

mdt-15 is not required for mitochondrial protein homeostasis. (A) Micrographs show control(RNAi), mdt-15(RNAi), WT, and mdt-15(tm2182) worms expressing the hsp-6p::GFP transcriptional reporter (Upper row) or the hsp-60p::GFP transcriptional reporter (Lower row). (B) Micrographs show control(RNAi) and mdt-15(RNAi) worms expressing the hsp-6p::GFP transcriptional reporter treated with 10 μg/mL antimycin A for 24 h (Lower row) or not treated (Upper row). For A and B, one of three independent experiments is shown. (C) Bars represent the relative abundance of individual FAs in cardiolipin (Left) and the average levels of cardiolipin relative to TLs or total PLs (Right). Lipids were extracted from control(RNAi) and mdt-15(RNAi) worms. n = 3; error bars represent SEM; *P < 0.05 as determined by two-tailed Student t test.