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The IL-1 receptor mediates GlyR LTP. (A) Representative example showing that after potentiation by IL-1β, GlyR IPSCs remain potentiated even in the presence of the IL-1 receptor antagonist, IL-1RN (2 mg/mL). (B) Average of seven experiments. (C) Single experiment illustrating that bath application of IL-1RN before IL-1β addition entirely prevented potentiation. (D) Average of five experiments. Error bars indicate mean ± SEM.
