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Effect of MSL-109 binding on glycoprotein interactions as monitored by TR-FRET. (A–C) FRET ratios calculated after addition of control IgG (white bar) or MSL-109 (black bar). FRET measured between (A) ST-gB and ACP-gH/gL, (B) ST-gH/gL and ACP-gH/gL, or (C) between ST-(HCN)gH/gL and ACP-(HCN)gH/gL. Data are means ± SEM of triplicates from three independent experiments.
