Table 4.
Synthetic multi-epitope peptides including MHC class I and II-restricted epitopes.
| Peptide name | Synthetic multi-epitope peptide sequence | Included epitopes | HLA supertype |
|---|---|---|---|
| CPA_p2 | 160-GNIEGQWALKNHSLVSLSEQVLVSCDNIDD-189 | 165-QWALKNHSL-173 | HLA-A2 (A*0201), HLA-A3 (A*03), HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 179-QVLVSCDNI-187 | |||
| 160-GNIEGQWAL-168 | |||
| 172-SLVSLSEQVLVSCDN-186 | |||
| 174-VSLSEQVLVSCDNID-188 | |||
| CPA_p3 | 273-LYFGGVVTLCFGLSLNHGVLVVGFNRQAKP-302 | 273-LYFGGVVTL-281 | HLA-A2 (A*0201), HLA-A3 (A*03), HLA-A24 (A*2402), HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 279-VTLCFGLSLNHGVLV-293 | |||
| 273-LYFGGVVTLCFGLSL-287 | |||
| H1_p1 | 1-MSSDSAVAALSAAMTSPQKS-20 | 2-SSDSAVAAL-10 | HLA-A2 (A*0201), HLA-A3 (A*03), HLA-DRB1, HLA-DQA1 |
| 1-MSSDSAVAALSAAMT-15 | |||
| 2-SSDSAVAALSAAMTS-16 | |||
| 5-SAVAALSAAMTSPQK-19 | |||
| H1_p3 | 43-AGAKKAGAKKAVRKVATPKK-61 | 46-KKAGAKKAV-54 | HLA-A2 (A*0201), HLA-A3 (A*03), HLA-DRB1 |
| 42-KAGAKKAGAKKAVRK-56 | |||
| 45-AKKAGAKKAVRKVAT-59 | |||
| KMP-11_p1 | 4-TYEEFSAKLDRLDEEFNRKM-23 | 4-TYEEFSAKL-12 | HLA-A3 (A*03), HLA-A24, HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 7-EFSAKLDRL-15 | |||
| 4-TYEEFSAKLDRLDEE-18 | |||
| LeIF_p1 | 6-KIAPQDQDSFLDDQPGVRPIPSFDDMPLHQ-35 | 8-APQDQDSFL-16 | HLA-B7 (B*5101), HLA-B15 (B62), HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 25-IPSFDDMPL-33 | |||
| 14-SFLDDQPGV-22 | |||
| 23-RPIPSFDDM-31 | |||
| 16-LDDQPGVRPIPSFDD-30 | |||
| LeIF_p3 | 181-DEMLSQGFADQIYEIFRFLPKDIQVALFSA-210 | 199-LPKDIQVAL-207 | HLA-B7 (B*3501, B*5101), HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 197-RFLPKDIQV-205 | |||
| 187-GFADQIYEI-195 | |||
| 195-IFRFLPKDI-203 | |||
| 199-LPKDIQVALFSATMP-213 | |||
| LeIF_p6 | 371-VTEKDVELLHEIEAHYHTQIDELPVDFAAY-400 | 385-HYHTQIDEL-393 | HLA-A3 (A*0301), HLA-A24, HLA-DRB1, HLA-DPA1, HLA-DQA1 |
| 393-LPVDFAAYL-401 | |||
| 320-VLVTTDLVARGICVH-334 | |||
| 387-HTQIDELPVDFAAYL-401 | |||
| 376-VELLHEIEAHYHTQI-390 |