Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Represented are domains within JAK2, including the FERM (4.1 protein, ezrin, radixin, moesin) domain, SH2 (Scr homology 2) like domain, the pseudokinase domain and the kinase domain (top), the JAK homology (JH) domains (middle) as well as regions that include hotspots for activating mutations and breakpoints for activating fusions (bottom).
