Table 2.
Biomarker Concentrations in Allograft Pump Perfusate by DGF Status
| Variable 1 | ALL (N=428) |
DGF (N=141) |
Non DGF (N=287) |
P 2 |
|---|---|---|---|---|
| Base pi-GST, ug/L | 191 [65–356] | 244 [76–399] | 176 [61–336] | 0.03 |
| Post pi-GST, ug/L | 498 [321–905] | 653 [394–980] | 446 [299–870] | 0.002 |
| Delta pi-GST, ug/L3 | 314 [145–601] | 368 [196–610] | 296 [124–595] | 0.05 |
| Base alpha-GST, ug/L | 147 [43–394] | 154 [66–413] | 140 [38–373] | 0.25 |
| Post alpha-GST, ug/L | 414 [218–800] | 506 [226–865] | 372 [215–748] | 0.06 |
| Delta alpha-GST, ug/L3 | 203 [81–481] | 220 [103–544] | 189 [69–406] | 0.07 |
| Renal resistance at 4 hrs, mmHg/ml/min |
0.23 [0.17–0.29] | 0.23 [0.19–0.32] | 0.22 [0.17–0.28] | 0.12 |
| Perfusate flow at 4 hrs, ml/min | 114 [94–132] | 111 [91–131] | 115 [99–133] | 0.13 |
Values are medians [interquartile range]. DGF, delayed graft function; GST, Glutathione S-transferase
1
For all perfusate biomarkers, base values were missing in 10 kidneys and post values were missing in 59 kidneys. Renal resistance and perfusate flow were missing in 106 kidneys.
2
Wilcoxon rank sum test (DGF vs. non-DGF)
3
Difference in post minus base values