Table 3.

Association of Perfusate Biomarkers with DGF

Biomarker	Time-point	Relative Risk (95% confidence interval) for DGF
		Unadjusted	Adjusted for donor variables only1	Adjusted for donor & transport variables 2	Adjusted for donor, transport & recipient variables 3
Pi-GST	Base	1.10 (0.98–1.22)	1.07 (0.96–1.19)	1.14 (1.01–1.27)	1.05 (0.96–1.16)
	Post	1.41 (1.13–1.77)	1.28 (1.02–1.61)	1.36 (1.05–1.75)	1.36 (1.14–1.63)
Alpha-GST	Base	1.06 (0.97–1.15)	1.04 (0.96–1.13)	1.09 (1.00–1.18)	1.03 (0.96–1.11)
	Post	1.14 (0.97–1.33)	1.03 (0.88–1.22)	1.09 (0.93–1.26)	1.11 (0.97–1.26)

Perfusate biomarkers were natural log-transformed and added individually to all models (i.e., perfusate biomarkers were not combined during multivariable adjustment). DGF, delayed graft function; GST, glutathione S-transferase.

¹Donor variables used for adjustment: age in years, Black race, DCD status, hypertension, diabetes, stroke as cause of death, terminal serum creatinine in mg/dl, height in cm, and weight in kg

²Includes donor variables listed above plus cold ischemia time in hours and renal resistance at 4 hours in mmHg/ml/min

³Includes all variables listed above (except renal resistance) plus the following recipient variables: Black race, male gender, previous kidney transplant, diabetes as the cause of end stage renal disease, need for pretransplant blood transfusion, number of human leukocyte antigen mismatches, body mass index in kg/m², and duration of dialysis before transplant in months