Table 4.
Biomarker |
Discarded Kidneys (N=128) |
Transplanted & DGF (N=141) |
Transplanted & Non-DGF (N=287) |
P-value (Discard vs. DGF) |
P-value (Discard vs. Non-DGF) |
---|---|---|---|---|---|
Base pi-GST, ug/L | 188 [42–337] | 243 [76.3–398.8] | 176 [61–335] | 0.07 | 0.90 |
Post pi-GST, ug/L | 580 [353–965] | 652 [394–980] | 446 [298–870] | 0.34 | 0.12 |
Base alpha-GST, ug/L | 93 [16–270] | 153 [66.3–412.5] | 140 [38–373] | 0.004 | 0.03 |
Post alpha-GST, ug/L | 303 [158–723] | 506 [225.6–865] | 372 [215–747.5] | 0.02 | 0.22 |
Renal resistance at 4 hrs, mmHg/ml/min |
0.29 [0.21–0.4] | 0.23 [0.19–0.32] | 0.22 [0.17–0.29] | <0.001 | <0.001 |
Perfusate flow at 4 hrs, ml/min |
93 [71–118] | 110 [91–131] | 114 [98–131] | <0.001 | <0.001 |
Values are medians [interquartile range]. DGF, delayed graft function; GST, glutathione S-transferase. P-values were obtained by Wilcoxon rank sum tests comparing discarded kidneys with transplanted kidneys that either did or did not develop DGF as indicated.