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. 2014 May 29;15:21. doi: 10.1186/1471-2172-15-21

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Copyright © 2014 Urry et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Depigmented-polymerised allergen extracts favour regulatory T cell-phenotype over effector phenotype. A Contour plots showing CD4⁺CD25⁺Foxp3^hi populations (regulatory phenotype) and CD4⁺CD25⁺Foxp3^low cells (effector phenotype) after 7-day culture with depigmented-polymerised (Depig-pol) or native HDM extracts. B Ratios of CD4⁺CD25⁺Foxp3^hi to CD4⁺CD25⁺Foxp3^low T cells from 7-day cultures stimulated with depigmented-polymerised or native extracts. N = 5, p values for paired t-test.