Table 4.
Odds Ratios for ILI occurrence in the study population in the 2010/11 influenza season as a function of demographic features, lifestyle, underlying diseases and drug use, n = 508 (Multivariable analysis – Hierarchical approach)
| |
Multivariable analysis |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Variables |
Adjusted OR
§
|
95% CI |
p
|
Adjusted OR
§
|
95% CI |
p
|
Adjusted OR
§
|
95% CI |
p
|
||||
| Level 1 | Level 2 | Level 3 | |||||||||||
|
Demographic features and lifestyle habits |
|
|
|
|
|
|
|
|
|
||||
| Aged 65 yrs or more* |
1.94 |
0.24;15.6 |
0.53 |
|
|
|
|
|
|
||||
| Smoking** |
0.64 |
0.37;1.14 |
0.13 |
|
|
|
|
|
|
||||
| Drinking**# |
3.04 |
1.22;7.59 |
0.02 |
2.17 |
0.87;5.51 |
0.09
^
|
2.10 |
0.87;4.94 |
0.10 |
||||
|
Underlying pathologies |
|
|
|
|
|
|
|
|
|
||||
| Cardiovascular diseases** |
0.34 |
0.14;0.83 |
0.02 |
0.56 |
0.22;1.39 |
0.21 |
|
|
|
||||
| Hypertension** |
1.26 |
0.68;2.35 |
0.47 |
|
|
|
|
|
|
||||
| Respiratory diseases** |
1.64 |
0.73;3.71 |
0.23 |
|
|
|
|
|
|
||||
| Diabetes** |
0.96 |
0.29;3.17 |
0.94 |
|
|
|
|
|
|
||||
| Cancer** |
1.08 |
0.15;7.93 |
0.94 |
|
|
|
|
|
|
||||
| Kidney diseases** |
0.61 |
0.14;2.71 |
0.51 |
|
|
|
|
|
|
||||
| Dyslipidaemia** |
0.17 |
0.07;0.42 |
0.0001 |
0.12 |
1.56 |
0.20 |
|
|
|
||||
| Gastric ulcer** |
0.20 |
0.07;0.54 |
0.002 |
1.18 |
0.31;4.57 |
0.82 |
|
|
|
||||
| Gastric diseases**° |
0.38 |
0.13;1.12 |
0.08
^
|
1.18 |
0.30;4.57 |
0.81 |
|
|
|
||||
|
Drugs taken |
|
|
|
|
|
|
|
|
|
||||
| Fibrates** |
|
|
|
0.08 |
0.05;1.41 |
0.09
^
|
0.03 |
0.01;0.50 |
0.02 |
||||
| Statins** |
|
|
|
0.28 |
0.07;1.15 |
0.08
^
|
0.15 |
0.05;0.43 |
<0.001 |
||||
| Antibiotics** |
|
|
|
1.75 |
0.53;5.79 |
0.36 |
|
|
|
||||
| Omeprazole family compounds** |
|
|
|
0.31 |
0.13;0.76 |
0.01 |
0.29 |
0.15;0.52 |
<0.001 |
||||
|
Vaccination status |
|
|
|
|
|
|
|
|
|
||||
| Influenza vaccination** | 0.31 | 0.16;0.58 | <0.001 | ||||||||||
§Conditional logistic regression models.
^As several variables were included in each level, only those variables reaching p < 0.1 were kept in the next step, in order to avoid unstable estimates in subsequent models.
*Reference: Less than 65 yrs.
**Reference: NO.
#Reference: More than 2 glasses of wine or more than one glass of spirits a day.
°Except Gastric ulcer.
The statistical significant p values are reported in bold.