Table 2.
Genes in the Streptococcus bovis / Streptococcus equinus complex potentially involved in lactose and galactose metabolism
| Function | Gene | S. gallolyticus UCN34 | S. gallolyticus ATCC 43143 | S. gallolyticus ATCC BAA-2069 | S. pasteurianus ATCC 43144 | S. macedonicus ACA-DC 198 | S. infantarius CJ18 |
|---|---|---|---|---|---|---|---|
| Lactose-specific PTS system repressor |
lacR |
GALLO_0176 |
SGGB_0220 |
SGGBAA2069_c01940 |
SGPB_0163 |
SMA_0197 |
Sinf_0181 |
| Galactose-6-phosphate isomerase, LacA subunit |
lacA |
GALLO_0177 |
SGGB_0221 |
SGGBAA2069_c01950 |
SGPB_0164 |
SMA_0198 |
Sinf_0182 |
| Galactose-6-phosphate isomerase, LacB subunit |
lacB1 |
GALLO_0178 |
SGGB_0222 |
SGGBAA2069_c01960 |
SGPB_0165 |
SMA_0199 |
Sinf_0183 |
| Tagatose-6-phosphate kinase |
lacC |
GALLO_0179 |
SGGB_0223 |
SGGBAA2069_c01970 |
SGPB_0166 |
SMA_0200 |
Sinf_0184 |
| Tagatose 1,6-diphosphate aldolase |
lacD2 |
GALLO_0180 |
SGGB_0224 |
SGGBAA2069_c01980 |
SGPB_0167 |
SMA_0201 |
Sinf_0185 |
| Putative PTS system, IIA component |
- (a) |
GALLO_0181 |
SGGB_0225 |
SGGBAA2069_c01990 |
SGPB_0168 |
SMA_0202 |
- |
| Putative PTS system, IIB component |
- |
GALLO_0182 |
SGGB_0226 |
SGGBAA2069_c02000 |
SGPB_0169 |
SMA_0203 |
- |
| Putative PTS system, IIC component |
- |
GALLO_0183 |
SGGB_0227 |
SGGBAA2069_c02010 |
SGPB_0170 |
SMA_0204 |
- |
| Aldose 1-epimerase |
lacX |
GALLO_0184 |
SGGB_0228 |
SGGBAA2069_c02020 |
SGPB_0171 |
SMA_0205 |
Sinf_0186 |
| Transcriptional antiterminator |
lacT |
GALLO_0185 |
SGGB_0229 |
SGGBAA2069_c02030 |
SGPB_0172 |
SMA_0206 |
Sinf_0187 (p) |
| |
|
|
|
|
|
|
Sinf_0188 (r) |
| |
|
|
|
|
|
|
Sinf_0189 |
| |
|
|
|
|
|
|
Sinf_0190 (p) |
| 6-phospho-beta-galactosidase |
lacG |
GALLO_0186 |
SGGB_0230 |
SGGBAA2069_c02040 |
SGPB_0173 |
SMA_0207 |
- |
| Transcriptional antiterminator |
lacT |
- |
- |
- |
- |
SMA_0208 (p) |
- |
| Lactose-specific PTS system, IIA component |
lacF |
GALLO_0187 |
SGGB_0231 |
SGGBAA2069_c02050 |
SGPB_0174 |
SMA_0209 |
Sinf_0191 |
| Lactose-specific PTS system, IIBC component |
lacE |
GALLO_0188 |
SGGB_0232 |
SGGBAA2069_c02060 |
SGPB_0175 |
SMA_0210 |
Sinf_0192 |
| 6-phospho-beta-galactosidase |
lacG2 |
- |
- |
- |
- |
SMA_0211 |
Sinf_0193 (p) |
| |
|
|
|
|
|
|
Sinf_0194 |
| |
|
|
|
|
|
|
Sinf_0195 (p) |
| Galactose repressor |
galR |
GALLO_0197 |
SGGB_0241 |
SGGBAA2069_c02150 |
SGPB_0184 |
SMA_0222 |
Sinf_0205 |
| Galactokinase |
galK |
GALLO_0198 |
SGGB_0242 |
SGGBAA2069_c02160 |
SGPB_0185 |
SMA_0223 |
Sinf_0206 |
| Galactose-1-P-uridyl transferase |
galT |
GALLO_0199 |
SGGB_0243 |
SGGBAA2069_c02170 |
SGPB_0186 |
SMA_0224 |
Sinf_0207 |
| UDP-glucose 4-epimerase |
galE |
GALLO_0200 |
SGGB_0244 |
SGGBAA2069_c02180 |
SGPB_0187 |
SMA_0225 |
Sinf_0208 |
| Beta-galactosidase |
lacZ |
- |
- |
- |
SGPB_0344 |
- |
- |
| Glucokinase |
glcK |
GALLO_0594 |
SGGB_0562 |
SGGBAA2069_c05300 |
SGPB_0467 |
SMA_0546 |
Sinf_0470 |
| Beta-galactosidase |
lacZ |
- |
- |
- |
- |
- |
Sinf_0935 |
| Lactose and galactose permease |
lacS |
- |
- |
- |
- |
- |
Sinf_0936 |
| Aldose 1-epimerase |
galM |
- |
- |
- |
- |
- |
Sinf_0937 |
| UDP-glucose 4-epimerase |
galE1 |
- |
- |
- |
- |
- |
Sinf_0938 |
| Galactose-1-P-uridyl transferase |
galT |
- |
- |
- |
- |
- |
Sinf_0939 (p) |
| UDP-glucose 4-epimerase |
lacS |
- |
- |
- |
- |
- |
Sinf_1514 |
| Aldose 1-epimerase |
lacX |
- |
- |
- |
- |
SMA_1156 |
- |
| 6-phospho-beta-galactosidase |
lacG2 |
- |
- |
- |
- |
SMA_1157 |
- |
| Lactose-specific PTS system, IIBC component |
lacE |
- |
- |
- |
- |
SMA_1158 |
- |
| Lactose-specific PTS system, IIA component |
lacF |
- |
- |
- |
- |
SMA_1159 |
- |
| Tagatose 1,6-diphosphate aldolase |
lacD |
- |
- |
- |
- |
SMA_1160 |
- |
| Tagatose-6-phosphate kinase |
lacC |
- |
- |
- |
- |
SMA_1161 |
- |
| Galactose-6-phosphate isomerase, LacB subunit |
lacB |
- |
- |
- |
- |
SMA_1162 |
- |
| Galactose-6-phosphate isomerase, LacA subunit |
lacA1 |
- |
- |
- |
- |
SMA_1163 |
- |
| Glucokinase |
glcK |
- |
- |
- |
- |
SMA_1164 |
- |
| Lactose phosphotransferase system repressor |
lacR |
- |
- |
- |
- |
SMA_1165 |
- |
| Transcription antiterminator |
lacT |
GALLO_1046 |
SGGB_1036 |
SGGBAA2069_c10230 |
SGPB_0907 |
- |
- |
| Lactose-specific PTS system, IIA component |
lacF |
GALLO_1047 |
SGGB_1037 |
SGGBAA2069_c10240 |
SGPB_0908 |
- |
- |
| Lactose-specific PTS system, IIBC component |
lacE |
GALLO_1048 |
SGGB_1038 |
SGGBAA2069_c10250 |
SGPB_0909 |
- |
- |
| Phospho-beta-galactosidase |
lacG |
GALLO_1049 |
SGGB_1039 |
SGGBAA2069_c10260 |
SGPB_0910 |
- |
- |
| Aldose 1-epimerase |
galM |
GALLO_0137 |
SGGB_0134 |
SGGBAA2069_c01550 |
SGPB_0130 |
- |
- |
| UDP-glucose 4-epimerase | galE1 | GALLO_0728 | SGGB_0709 | SGGBAA2069_c06910 | SGPB_0601 | - | - |
(a) Not found; (p) Pseudogenes; (r) Transposase genes in italics.