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. 2014 Apr 8;15:272. doi: 10.1186/1471-2164-15-272

Table 5.

Genes in the Streptococcus bovis / Streptococcus equinus complex identified as putative virulence factors

Virulence factor Gene S. gallolyticus UCN34 S . gallolyticus ATCC 43143 S . gallolyticus ATCC BAA-2069 S. pasteurianus ATCC 43144 S. macedonicus ACA-DC 198 S . infantarius CJ18
Pilus 1 (pil1)
acb
GALLO_2179
SGGB_2211
SGGBAA2069_c21760
- (a)
-
-
 
sbs7
GALLO_2178
SGGB_2210
SGGBAA2069_c21750
SGPB_1938 (p)
-
-
 
srtC1
GALLO_2177
SGGB_2209
SGGBAA2069_c21740
-
-
Sinf_1876
Pilus 2 (pil2)
-
GALLO_1570
SGGB_1568
SGGBAA2069_c15960
-
-
-
 
-
GALLO_1569
SGGB_1567
SGGBAA2069_c15950
-
-
-
 
-
GALLO_1568
SGGB_1566
SGGBAA2069_c15940
-
-
-
Pilus 3 (pil3)
sbs15
GALLO_2040
SGGB_2022
SGGBAA2069_c19980
SGPB_1847
SMA_1939
Sinf_1744
 
sbs14
GALLO_2039
SGGB_2021
SGGBAA2069_c19970
SGPB_1846
SMA_1938
Sinf_1743
 
srtC3
GALLO_2038
SGGB_2020
SGGBAA2069_c19960
SGPB_1845
SMA_1937
Sinf_1742
Cell envelope proteinase (lactocepin)
sbs6
GALLO_0748
SGGB_0730
SGGBAA2069_c07210
-
-
Sinf_0588
Fructan hydrolase
sbs10
GALLO_0112
SGGB_0110
SGGBAA2069_c01280
-
-
-
Collagen adhesin
sbs13
GALLO_2032
SGGB_2016
SGGBAA2069_c19910
SGPB_1839 (p)
SMA_1932 (s)
Sinf_1737 (p)
 
 
 
 
 
SGPB_1840 (p)
SMA_1933 (p)
 
 
 
 
 
 
 
SMA_1934 (s)
 
Collagen adhesin
sbs16
GALLO_0577
SGGB_0544
SGGBAA2069_c05110
-
-
-
Cell surface protein antigen C (PAc)
-
GALLO_1675
SGGB_0154
SGGBAA2069_c13880
-
-
-
 
 
 
SGGB_1687
SGGBAA2069_c20560
 
 
 
Surrface-exposed histone-like protein A
hlpA
GALLO_0636
SGGB_0611
SGGBAA2069_c05790
SGPB_0505
SMA_0597
Sinf_0517
Autolysin
atlA
GALLO_1368
SGGB_1362
SGGBAA2069_c13580
SGPB_1289
SMA_1299
Sinf_1186 (t)
Glucan biosynthesis gene cluster
-
GALLO_1052
-
SGGBAA2069_c10370
-
-
-
 
-
GALLO_1053
SGGB_1042
SGGBAA2069_c10380
-
-
-
 
rggA
GALLO_1054
SGGB_1043
SGGBAA2069_c10390
-
-
Sinf_0876
 
gtfA
GALLO_1055
SGGB_1044
SGGBAA2069_c10400
-
-
Sinf_0877
 
rggB
GALLO_1056
SGGB_1045
SGGBAA2069_c10410
-
-
-
 
gtfB
GALLO_1057
SGGB_1046
SGGBAA2069_c10420
-
-
-
 
sbs2/gbpC
GALLO_1058
SGGB_1047
SGGBAA2069_c10430
-
SMA_0989 (p)
-
 
 
 
 
 
 
SMA_0990 (s)
 
 
 
 
 
 
 
SMA_0991 (s)
 
Hemicellulose biosynthesis gene cluster
-
GALLO_0364
SGGB_0392
SGGBAA2069_c03530
-
SMA_0392 (p)
Sinf_0344
 
-
GALLO_0365
SGGB_0393 (p)
SGGBAA2069_c03540 (s)
-
SMA_0393 (p)
-
 
 
 
SGGB_0394 (p)
SGGBAA2069_c03550 (s)
 
 
 
 
-
GALLO_0366
SGGB_0395
SGGBAA2069_c03560
-
SMA_0394 (p)
Sinf_0345
 
 
 
 
 
 
 
Sinf_0346 (s)
 
-
GALLO_0367
SGGB_0396
SGGBAA2069_c03570
-
-
-
Hemolysin TLY
-
GALLO_0630
SGGB_0605
SGGBAA2069_c05730
SGPB_0499
SMA_0591
Sinf_0511
Hemolysin III
-
GALLO_1262
SGGB_1256
SGGBAA2069_c12530
SGPB_1172
SMA_1191
Sinf_1093
Hemolysin A family protein
-
GALLO_1799
SGGB_1786
SGGBAA2069_c17570
SGPB_1603
SMA_1706
Sinf_1530
Exfoliative toxin B
-
-
-
-
-
-
Sinf_0933
Macrophage infectivity potentiator protein - - - - - - Sinf_0931

(a) Not found; (p) Pseudogenes; (s) Split CDSs corresponding to fragments of the original gene not yet characterized as pseudogenes; (t) Truncated.