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Long-term human hematopoietic cell reconstitution in NOG mice. A total of 5 × 103 18Lin−CD34+/−CD133+/− cells (a and b) was injected into the left tibiae of NOG mice by IBMI. The human CD45+ cell rates in the contralateral sites of recipient mice were serially analyzed by the BM aspiration method 6, 12 and 18 weeks after transplantation by six-color FCM. The data represent the means±s.d. of the results from five or six mice at each time point.
