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. Author manuscript; available in PMC: 2015 Apr 25.
Published in final edited form as: Int J Pharm. 2014 Feb 7;465(0):52–62. doi: 10.1016/j.ijpharm.2014.01.043

Table 8.

The effect of orifice size (3.1 vs. 2.3 mm) and 3D rod configuration on the mean AS emitted dose and aerosolization performance with four bag actuations. The data for the 3.1–565-ECG device is taken from Table 1 for comparison.

Description 3.1–565-ECG 2.3–343-ECG 2.3–212-ECG
ED (%) 71.1 (1.0) 75.3 (2.5) 68.8 (4.4)
FPF<5μm/ED (%)* 83.1 (1.4) 65.4 (6.4)** 60.2 (8.5)**
FPF<1μm/ED (%)* 30.3 (1.6) 20.7 (3.0)** 21.1 (4.7)**
MMAD (μm)* 1.39 (0.05) 1.64 (0.07)** 1.59 (0.07)**
*

P<0.05 significant effect of device on % FPF<5μm/ED, FPF<1μm/ED and MMAD (one-way ANOVA).

**

P<0.05 significant differences compared to 3.1–565-ECG (post-hoc Tukey).