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. 2014 Apr 23;11(6):1880–1888. doi: 10.1021/mp500014r

Figure 3.

Figure 3

Effect of LPS (10 ng/mL) induction time on the expression of mPhT2/hPhT2, IL-6, and TNFα mRNA in J77A.1 and THP-1 macrophages. In J774A.1 cells (A), mPhT2, IL-6, and TNFα mRNA were increased when treated with LPS for 2, 3, and 4 h. In THP-1 cells (B), hPhT2, IL-6, and TNFα mRNA were also increased when treated with LPS for 2, 3, and 4 h. Data are expressed as mean ± SD, n = 3. Statistical analyses were performed by one-way ANOVA and Dunnett’s test. *p < 0.05, **p < 0.01, and ***p < 0.001 as compared to control. CON = control group.