Figure 5.
mRNA expression of mPhT2, TNFα, and IL-6 in mouse spleen induced by LPS. (A) mPhT2 mRNA was significantly increased in spleen when mice were injected with LPS (1.0 mg/kg i.p.) and samples obtained 2, 4, and 6 h after the injection. (B,C) IL-6 and TNFα mRNA were also up-regulated by LPS in mouse spleen. Data are expressed as mean ± SD, n = 4. Statistical analyses were performed by one-way ANOVA and Dunnett’s test. ** p < 0.01 and ***p < 0.001 as compared to control. CON = control group.