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Mb aggregation in lyophilized formulations during stability study, as monitored using DLS and HP-SEC. The increase in particle size for formulations stored at 25 °C (A) and 40 °C (B) and the percentage loss of monomeric Mb for formulations stored at 25 °C (C) and 40 °C (D) were plotted against time (n = 3, ±SE). MbA (closed circle), MbB (closed triangle), MbC (open circle), MbD (open square), and MbE (closed square).
