. 2012 Nov 8;34(25):1930–1941. doi: 10.1093/eurheartj/ehs375

Table 2.

Synd-1 and MMP-9 protein levels in relation to rejection grades on endomyocardial biopsy

	Grade 0 (n = 21)	Grade 1A (n = 19)	Grade 1B (n = 16)	Grade 3 (n = 15)	ANOVA post-test for linearity
	Grade 0 (n = 21)	Grade 1A (n = 19)	Grade 1B (n = 16)	Grade 3 (n = 15)	R²-value	P-value
Synd-1, %	2.04 ± 0.5	4.07 ± 0.75	5.24 ± 1.34*	12.89 ± 3.36,,**	0.692	<0.0001
MMP-9, %	0.12 ± 0.07	0.35 ± 0.57	0.79 ± 0.61*	1.67 ± 2.03,,**	0.240	<0.0001

Protein levels are given as percentage of the positive staining area relative to the total tissue area and presented as mean ± SD. N = 71, including n = 21 for ISHLT Grade 0 collected from 21 patients, n = 19 for Grade 1A from 19 patients, n = 16 for Grade 1B from 15 patients and n = 15 for Grade 3 from 12 patients.

EMB, endomyocardial biopsy; Synd-1, syndecan-1; MMP, matrix metalloproteinase.

*P < 0.05 vs. Grade 0.

**P < 0.05 vs. Grade 1A.

***P < 0.05 vs. Grade 1B.