Table 2. LPS Treatment Caused Splenomegaly.
Control | Clopidogrel | LPS | LPS + clopidogrel | |
---|---|---|---|---|
WT | 0.5 ± 0.1 | 0.40 ± 0.02 | 1.0 ± 0.1a | 1.5 ± 0.1a |
KO | 0.23 ± 0.04 | 0.54 ± 0.12 | 1.0 ± 0.2a | 1.0 ± 0.1a |
Spleen weight was analyzed in WT and KO animals, untreated or treated with clopidogrel, LPS, and LPS plus clopidogrel. Data are expressed in mg/g weight.
P < 0.05 (LPS treated vs. control; LPS plus clopidogrel vs. clopidogrel only; n=9).