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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: J Am Chem Soc. 2014 Jan 3;136(2):741–749. doi: 10.1021/ja410824x

Figure 5.

Figure 5

Molar ellipticity at the exciton couplet maximum (228 nm) versus temperature for three WW sequence mutants. The steeper pre-melting slope for the circular permutant likely reflects greater Trp χ angle variation with warming when the EtF Trp/Trp unit involves the chain terminal residues rather than being at a sequence-internal, turn-flanking position.