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. Author manuscript; available in PMC: 2014 Aug 20.
Published in final edited form as: Nature. 2014 Jan 5;506(7488):387–390. doi: 10.1038/nature12891

Extended Data Figure 3. Transcriptional profiling of C. lusitaniae wildtype and ime2Δ mutants during mating and meiosis.

Extended Data Figure 3

a, Full profile of wildtype and ime2Δ/ime2Δ strains during meiosis indicates that many transcriptional changes occur in ime2Δ/ime2Δ mutants as in wildtype strains. b, Analysis of cell cycle regulating genes during C. lusitaniae meiosis. Several cell cycle genes are induced in wildtype cells undergoing meiosis but not in ime2Δ/ime2Δ mutants (e.g., APC4, CDC3, CDC10, and CDC14). c, Comparative expression of early (IME2, IME4, SPO11), middle (REC102, CDC3, SPS4, SPS1, NDT80, SWM1) and late (DIT1, DIT2) meiosis genes. d, In contrast to the meiotic profiles, the mating profiles of wildtype and ime2Δ strains were very similar. e, Comparison of meiosis genes induced in wildtype and ime2Δ mutants.