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. Author manuscript; available in PMC: 2014 Aug 20.
Published in final edited form as: Nature. 2014 Jan 5;506(7488):387–390. doi: 10.1038/nature12891

Extended Data Figure 4. Reintegration of IME2 restores mating efficiency.

Extended Data Figure 4

IME2 was reintegrated at the endogenous locus in an ime2Δ mutant (RSY437). Mating frequency was quantified by monitoring the formation of prototrophic products from auxotrophic parents. WT cross, RSY411 x RSY284, ime2Δ mutant cross, RSY406 x RSY437, IME2 complemented cross, RSY406 x CAY5022. Differences between the WT cross and the ime2Δ mutant cross, and between the IME2 complemented cross and the ime2Δ mutant cross were both significant. (n=7, p < 0.001, Kruskal Wallis test). Data are representative of mean +/- s.e.m.