Table 1.
Potential risk factors of study subjects
| Potential risk factors | Cases, n (%) | Controls, n (%) | p value* |
|---|---|---|---|
| Age (tertile), years | |||
| < 59 | 96 (28.7) | 266 (33.8) | |
| 60-65 | 119 (35.6) | 236 (29.9) | |
| > 65 | 119 (35.6) | 286 (36.3) | 0.12 |
| Sex | |||
| Female | 66 (19.8) | 150 (19.0) | |
| Male | 268 (80.2) | 638 (81.0) | 0.78 |
| Ever-smoker | |||
| No | 156 (47.4) | 590 (75.4) | |
| Yes | 173 (52.6) | 193 (24.6) | < 0.001 |
| Body mass index (tertile), kg/m2 | |||
| < 22.0 | 97 (29.1) | 262 (33.2) | |
| 22.0-25.4 | 122 (36.5) | 264 (33.6) | |
| > 25.4 | 115 (34.4) | 262 (33.2) | 0.36 |
| Total cholesterol (tertile), mmol/L | |||
| < 2.9 | 57 (17.1) | 262 (33.2) | |
| 2.9-4.8 | 123 (36.8) | 263 (33.4) | |
| > 4.8 | 154 (46.1) | 263 (33.4) | < 0.001 |
| Triglyceride (tertile), mmol/L | |||
| < 1.1 | 113 (33.8) | 265 (33.7) | |
| 1.1-1.6 | 111 (33.2) | 258 (32.8) | |
| > 1.6 | 110 (33.0) | 263 (33.5) | 0.98 |
| Homocysteine (tertile), μmol/L | |||
| < 9 | 70 (21.6) | 241 (32.3) | |
| 9-11 | 106 (32.7) | 252 (33.7) | |
| > 11 | 148 (45.7) | 254 (34.0) | < 0.001 |
| Hypertension | |||
| No | 128 (38.3) | 520 (66.0) | |
| Yes | 206 (61.7) | 268 (34.0) | < 0.001 |
| Diabetes | |||
| No | 212 (63.5) | 638 (81.0) | |
| Yes | 122 (36.5) | 150 (19.0) | < 0.001 |
| Mean LINE-1 (SD) | 80.96 (2.40) | 81.67 (2.46) | < 0.001† |
SD: standard deviation.
*
P value obtained from a X2-test comparing cases and controls.
†
P value obtained from a Student's t-test comparing cases and controls.